effects of t-2 toxin on cytokine produc-tion by mice peritoneal macrophages and lymph node t-cells
نویسندگان
چکیده
background: t-2 toxin is a mycotoxin of type a trichothecenes produced by several fungal genera such as fusarium species. mycotoxins can affect both cell mediated and humoral immune compartments. objective: the purpose of this study was to investi-gate the effect of t-2 toxin on cytokine production by mouse peritoneal macrophages and lymph node t cells. methods: mouse peritoneal macrophages and lymph node t cells were isolated and treated with different concentrations of t-2 toxin and incubated at 370c and 5% co2 in air for 48 hours. cell free media were removed and used for cy-tokine assay by an elisa method. results: t-2 toxin significantly reduced il-1β re-lease in a concentration dependent manner (p
منابع مشابه
Effects of T-2 Toxin on Cytokine Produc-tion by Mice Peritoneal Macrophages and Lymph Node T-Cells
Background: T-2 toxin is a mycotoxin of type A trichothecenes produced by several fungal genera such as Fusarium species. Mycotoxins can affect both cell mediated and humoral immune compartments. Objective: The purpose of this study was to investi-gate the effect of T-2 toxin on cytokine production by mouse peritoneal macrophages and lymph node T cells. Methods: Mouse peritoneal macrophages and...
متن کاملEffects of T-2 toxin on cytokine production by mice peritoneal macrophages and lymph node T-cells.
BACKGROUND T-2 toxin is a mycotoxin of type A trichothecenes produced by several fungal genera such as Fusarium species. Mycotoxins can affect both cell mediated and humoral immune compartments. OBJECTIVE The purpose of this study was to investigate the effect of T-2 toxin on cytokine production by mouse peritoneal macrophages and lymph node T cells. METHODS Mouse peritoneal macrophages and...
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عنوان ژورنال:
iranian journal of immunologyجلد ۵، شماره ۳، صفحات ۱۷۷-۱۸۰
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